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Everything You Should Know About Urolithin Supplements

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  What is urolithin? Urolithin   is a human microbial metabolite of ellagic acid derivatives in the diet, such as ellagitannin. They are produced in the human intestine, after absorbing foods containing ellagitannins (such as pomegranates, strawberries, red raspberries, walnuts or wine aged in oak barrels) in the form of urolithin B glucuronic acid Found in urine. During the metabolism of bacteria through the intestine, ellagitannins and punicalagins are converted into urolithins, and their biological activity in the human body is unknown. The urolithin metabolites of pomegranate juice ellagitannin are exclusively located in the prostate, colon and intestinal tissues of mice. Ellagitannin shows low bioavailability and is converted into ellagic acid and its microbiota metabolites in the intestine. Urolithin is mainly found in low concentration of glucuronide in plasma. The production of urolithin depends on the intestinal type of the intestinal microbiome. Individuals that prod...

Antioxidant Urolithin B: Is it good for us?

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  What is Urolithin B ? Urolithin B powder? Urolithin B  powder ( CAS NO :1139-83-9) is an urolithin, a type of phenolic compounds produced in the human gut after absorption of ellagitannins-containing food such as pomegranate,strawberries, red raspberries, walnuts or oak-aged red wine. Urolithin B is found in the urine in the form of urolithin B glucuronide. Urolithin B decreases protein degradation and induces muscle hypertrophy. Urolithin B inhibits the activity of aromatase, an enzyme that interconverts estrogen and testosterone. Urolithin B is a natural product with antiproliferative and antioxidant activity. Urolithin B has been shown to cross the blood brain barrier, and may have neuroprotective effects against Alzheimer’s Disease. Urolithin B is an intestinal microbial metabolite of ellagitannis and exhibits potent anti-oxidant and pro-oxidant activies depending on the assay system and conditions. Urolithin B can also display estrogenic and/or anti-estrogenic activity....