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Everything You Should Know About Urolithin Supplements

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  What is urolithin? Urolithin   is a human microbial metabolite of ellagic acid derivatives in the diet, such as ellagitannin. They are produced in the human intestine, after absorbing foods containing ellagitannins (such as pomegranates, strawberries, red raspberries, walnuts or wine aged in oak barrels) in the form of urolithin B glucuronic acid Found in urine. During the metabolism of bacteria through the intestine, ellagitannins and punicalagins are converted into urolithins, and their biological activity in the human body is unknown. The urolithin metabolites of pomegranate juice ellagitannin are exclusively located in the prostate, colon and intestinal tissues of mice. Ellagitannin shows low bioavailability and is converted into ellagic acid and its microbiota metabolites in the intestine. Urolithin is mainly found in low concentration of glucuronide in plasma. The production of urolithin depends on the intestinal type of the intestinal microbiome. Individuals that prod...
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Antioxidant Urolithin B: Is it good for us?

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  What is Urolithin B ? Urolithin B powder? Urolithin B  powder ( CAS NO :1139-83-9) is an urolithin, a type of phenolic compounds produced in the human gut after absorption of ellagitannins-containing food such as pomegranate,strawberries, red raspberries, walnuts or oak-aged red wine. Urolithin B is found in the urine in the form of urolithin B glucuronide. Urolithin B decreases protein degradation and induces muscle hypertrophy. Urolithin B inhibits the activity of aromatase, an enzyme that interconverts estrogen and testosterone. Urolithin B is a natural product with antiproliferative and antioxidant activity. Urolithin B has been shown to cross the blood brain barrier, and may have neuroprotective effects against Alzheimer’s Disease. Urolithin B is an intestinal microbial metabolite of ellagitannis and exhibits potent anti-oxidant and pro-oxidant activies depending on the assay system and conditions. Urolithin B can also display estrogenic and/or anti-estrogenic activity....
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Supplements Urolithin A Reviews: Definition, Mechanism, Benefits & Side Effects

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What is Urolithin A? Urolithin A is a metabolite compound resulting from the transformation of ellagitannins by the gut bacteria. It belongs to the class of organic compounds known as benzo-coumarins or dibenzo-α-pyrones. Urolithin A has been demonstrated to stimulate mitophagy and improve muscle health in old animals and in preclinical models of aging. Meanwhile, it also has been shown to cross the blood brain barrier, and may have neuroprotective effects against Alzheimer’s Disease. Urolithin A powder is a natural product with antiproliferative and antioxidant activity. Urolithin A is formed by metabolism from polyphenols found in some nuts and fruits, particularly pomegranates. Its precursors – ellagic acids and ellagitannins – are ubiquitous in nature, including edible plants, such as pomegranates, strawberries, raspberries, walnuts, tea and muscat grapes, as well as many tropical fruits. Since the 2000s, urolithin A has been subject of preliminary studies regarding its possible bi...
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Urolithin A powder wholesale buy CAS 1143-70-0

  Urolithin A（1143-70-0） Specifications Product Name Urolithin A powder Chemical Name 3,8-dihydroxy-6H-benzo[c]chromen-6-one; 3,8-Dihydroxy-6H-dibenzo(b,d)pyran-6-one; 3,8-Dihydroxyurolithin; 3,8-dihydroxybenzo[c]chromen-6-one; 6H-Dibenzo[b,d]pyran-6-one, 3,8-dihydroxy-; 3,8-Hydroxydibenzo-alpha-pyrone; CAS Number 1143-70-0 InChIKey RIUPLDUFZCXCHM-UHFFFAOYSA-N SMILES C1=CC2=C(C=C1O)C(=O)OC3=C2C=CC(=C3)O Molecular F ormula C13H8O4 Molecular W eight 228.2 g/mol Monoisotopic Mass 228.042259 g/mol Melting point 340-345 °C Boiling point  527.9±43.0 °C(Predicted) Flash Point 214.2ºC Biological Half-Life Urolithin A is present in urine up to 48 hours after pomegranate juice consumption. Color White to beige S olubility  DMSO: 20 mg/mL, clear S torage T emperature  2-8°C A pplication Used as a food supplement and anti-aging product, can be used to reduce inflammation and fight cancer;   What is Urolithin A? Urolithin A is a metabolite compound resulting from the transfo...
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